Biotransformations in organic chemistry. A textbook, third edition, by Kurt Faber, Springer‐Verlag, Berlin, , pp. Yuri Khmelnitsky. Biotransformations in Organic Chemistry: A Textbook, 5th Edition by Kurt Faber. Springer-Verlag: Heidelberg. + XI pp. £27 (paperback). Description. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective.
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After a basic introduction into the use of biocatalysts – principles of stereoselective transformations, kinetics and enzyme properties – the different types of reactions are explained according to the ‘reaction principle’, such as hydrolysis, reduction, oxidation, C-C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques and the use of modified enzymes, are treated in a separate biotransformatoons.
In this revised and corrected 5th edition, emphasis has been given to an improved didactic style in order to facilitate a deeper understanding of the underlying principles.
Kinetics, equilibria, and their effects on selectivity and enantioselectivity are explained in careful detail, with interesting reactions provided to exemplify these concepts. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry.
Book Review: Biotransformations in Organic Chemistry – Kurt Faber
Nonetheless, it enumerates all of the im important aspects, and in this regard will be of interest to the researcher who wishes to begin working in the field of biotransformations. This book is not a reference work, though, since it includes explanations of the many reaction classes such as hydrolysis, reduction, oxidation, etc.
A final chapter deals with the basic rules for the safe and practical lurt of biocatalysts. This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field.
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Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this book, Kurt Faber, who holds the position of Dozent at this institution, has produced an outstanding teaching aid in the area of biotransformations. Introduction and Background Information: Biotrajsformations developments, such as dynamic resolution, stereo-inversion and enantio-convergent processes are included.