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Detection and Serogrouping of Dichelobacter nodosus Infection by Use of Direct PCR from Lesion Swabs To Support Outbreak-Specific Vaccination for Virulent. Dichelobacter nodosus, Small ( mm in diameter) translucent grayish white colonies after days. Grows slowly and the colonies are. The aim of this study was to determine the proportion of Dichelobacter nodosus, Fusobacterium necrophorum and Treponema spp. in sheep.

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It is a pathogenic, anaerobic, non-spore-forming Gram-negative bacteria.

It causes footrot in sheep, along with other bacteria. They have long, polar fimbriae. There are 16 antigenic types of fimbriae, which can be used to differentiate strains antigenically. All of the strains possess the same O antigen. Colonies of virulent strains have a dark central zone, a pale granular middle zone noeosus an irregular periphery.

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Dichelobacter nodosus – WikiVet English

Thermostable proteases and elastase contribute to the pathogenesis of Dichelobactrr. Keratinolytic proteases are required for virulence and fimbriae are required for adhesion to hoof.

It can be passed from animal to animal. A homologous antibody to the fimbrial antigen prevents adhesion and protects against D.

The antibody must penetrate the epidermal layers and reach adequate concentration on the skin surface. A vaccine is available against D. For more information on Contagious Footrot.

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